Kimberly Rizzolo
Company: Novartis
Job title: Principal Scientist
Seminars:
De-Risking Kinase Preclinical Studies: Translating Biochemical Data Into Cellular Selectivity 8:30 am
Shifting away from isolated kinases to comprehend their larger complexes and their interactions Depicting how structural changes within kinase complexes influence target activation and modulation Evaluating the impact of post-translational modifications on assembly, stability, and functionalityRead more
day: Conference Day One
Panel Discussion: The Kinome Kit – Augmenting Selectivity Profiling Through Assays to Achieve On-Target Specificity 2:00 pm
Evaluating compounds against other kinases to identify potential off-target effects in early development Employing continuous assay systems to access full enzymatic activity over time and monitor various mechanisms of action Uncovering strategies for detecting kinase selectivity to facilitate effective target engagement and improve drug efficacyRead more
day: Conference Day One